Standardization of an experimental murine model of invasive pulmonary aspergillosis.
نویسندگان
چکیده
Evaluating new therapeutic agents for invasive aspergillosis requires animal models that are reproducible among different laboratories. We therefore evaluated a murine model of aerosol infection in two independent laboratories and found a high level of both intra- and interlaboratory reproducibility of survival, fungal burden over time, and the efficacy of liposomal amphotericin B.
منابع مشابه
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عنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 50 10 شماره
صفحات -
تاریخ انتشار 2006